High resolution two-dimensional electrophoresis of human plasma proteins.
نویسندگان
چکیده
The two-dimensional electrophoretic technique of O'Farrell has been adapted to the analysis of human plasma proteins, and 30 polypeptides have been identified in the pattern produced. Genetic variants involving charge (isoelectric point) or size (molecular weight in the presence of sodium dodecyl sulfate) changes should be routinely detectable in at least 20 proteins at once, facilitating studies of human mutation rates.
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عنوان ژورنال:
- Proceedings of the National Academy of Sciences of the United States of America
دوره 74 12 شماره
صفحات -
تاریخ انتشار 1977